For many disease-causing proteins, there are no known classical binding sites, so there’s been no way to develop small-molecule drugs to intervene. Frontier uses quantitative proteomics and machine learning to find pockets where small molecules can bind covalently, opening up formerly undruggable targets such as KRAS, a molecular switch driving many forms of cancer.
Explore Companies
Radionetics Oncology
Discovering more precise ways to deploy radiopharmaceuticals against solid tumors
DVLP Medicines
Creating a software co-pilot for drug development and a new marketplace for investors and outsourced R&D and manufacturing
Noetik
Using self-supervised machine learning to map the circuit diagram of tumor biology and develop new immunotherapies for cancer
Solu Therapeutics
Advancing precision medicine by combining the efficacy of antibodies with the binding ability of small molecules