Our fourth annual Deep Tech Opportunities Report reflects our partnership’s determination of the most compelling opportunities across deep tech — from energy, computing and AI, quantum, and manufacturing to drug discovery, robotics, and defense. This year’s theme — “Back to Fundamentals in an Age of Exponential Change” — is a direct response to intensifying unpredictability and the need across industries for a reset in core areas of technology.
In this report
Deep Tech Opportunities report 2026
Introduction
Back to Fundamentals in an Age of Exponential Change: Introduction
Deep Tech Opportunities report 2026
Opportunity 0.1
A few words on the investing climate
Deep Tech Opportunities report 2026
Chapter 1.0
We must reinvent classical computing—and physical AI—for an era of rapid scale-up.
Deep Tech Opportunities report 2026
Opportunity 1.1
Next-gen lithographic techniques and smarter chip architectures will help rein in AI’s power requirements.
Deep Tech Opportunities report 2026
Chapter 2.0
Quantum computing is evolving from a lab experiment into an industrial stack.
Deep Tech Opportunities report 2026
Opportunity 2.1
The effort to build reliable hardware to hold qubits is not a winner-take-all race
Deep Tech Opportunities report 2026
Opportunity 2.2
Advanced error detection and correction are critical elements in the quantum revolution
Deep Tech Opportunities report 2026
Opportunity 2.3
We don’t need to wait for fault-tolerant quantum computing to achieve “quantum advantage”
Deep Tech Opportunities report 2026
Chapter 3.0
In energy and climate, deep tech innovation is our best shot at limiting the cost of growth
Deep Tech Opportunities report 2026
Opportunity 3.1
New approaches are unlocking geothermal power in places that were previously thought uneconomic
Deep Tech Opportunities report 2026
Opportunity 3.2